Duke Innovation Digest

Research, ventures, and the people moving Duke innovation forward.

Duke Innovation Digest

Research, ventures, and the people moving Duke innovation forward.

Duke Innovation Digest

Duke alum trains next generation of founders to learn from failure

Upswing co-founder and CEO Melvin Hines, a Duke JD/MBA alum, returned to campus to let Executive MBA students dissect a case study of his edtech startup's toughest choices, sharing lessons on funding, hiring, and building a company without personal wealth.

· 1 min read

Duke alum trains next generation of founders to learn from failure

Upswing co-founder and CEO Melvin Hines, a Duke JD/MBA alum, returned to campus to let Executive MBA students dissect a case study of his edtech startup's toughest choices, sharing lessons on funding, hiring, and building a company without personal wealth.

· 1 min read

Duke alum trains next generation of founders to learn from failure

Upswing co-founder and CEO Melvin Hines, a Duke JD/MBA alum, returned to campus to let Executive MBA students dissect a case study of his edtech startup's toughest choices, sharing lessons on funding, hiring, and building a company without personal wealth.

· 1 min read

Breakthroughs

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Breakthroughs

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Breakthroughs

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Two researchers in white lab coats examining a glass slide in a laboratory, one wearing blue gloves and glasses.

Duke researchers discover how two proteins manage hundreds of drug targets

Duke School of Medicine researchers published a Nature study showing that β-arrestin proteins form liquid-like droplet clusters that regulate G protein-coupled receptors, the targets of one-third of FDA-approved drugs, potentially pointing toward new approaches in drug design.

Ventures

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Ventures

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Ventures

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Duke alum trains next generation of founders to learn from failure

Upswing co-founder and CEO Melvin Hines, a Duke JD/MBA alum, returned to campus to let Executive MBA students dissect a case study of his edtech startup's toughest choices, sharing lessons on funding, hiring, and building a company without personal wealth.

Duke brothers' sports app hits 1 million daily users without spending a dollar on ads

John Antonelli, a 2023 Duke computer science graduate and participant in Duke's Melissa & Doug Entrepreneurs program, co-founded the fan-engagement app Real with his brothers. The platform peaked at 1 million daily active users during Game 7 of the NBA Western Conference Finals, capping growth from 9,000 monthly users in late 2021.

Innovators

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Innovators

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Innovators

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How two Duke PhD students built a regional biotech launchpad

Zack Weaver and Victoria Goldenshtein, the first PhD students in Duke's Tadross Lab, co-founded the Research Triangle Park chapter of Nucleate in 2021 to support early-stage life-science entrepreneurs; the chapter remains active in 2026 with ongoing programming and industry partnerships.

Duke PhD student turns poo collection data into children's nutrition tool

Duke PhD graduate Ammara Aqeel adapted ecological DNA metabarcoding to track children's diets from stool samples, won $6,500 in a Duke accelerator, and filed an invention disclosure for a diet-tracking tool aimed at dietitians before completing her degree in May 2025.

Impact

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Impact

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Impact

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Editor's Picks

Editor's Picks

Editor's Picks

Duke researcher says glucagon, not just GLP-1, may be driving obesity drugs' record weight loss results

Duke's Jonathan Campbell presented evidence at ADA 2026 that glucagon, not just GLP-1, may be a key driver behind the remarkable efficacy of triple-agonist obesity drugs like retatrutide, which produced up to 30% body weight loss in Phase 3 trials.

A man in glasses and a maroon shirt observes a woman in a white lab coat working with laboratory equipment.

About the Editor

About the Editor

About the Editor

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